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Recently, it was shown that cysteine uptake via excitatory amino acid carrier 1 suppresses ischemia-induced neuronal death through promotion of hippocampal GSH synthesis in ischemic animal models (162)
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Experimental investigations have examined interactions between glutathione-dependent redox systems, Nrf2-associated signaling mechanisms, and the regulation of enzymes involved in glutathione biosynthesis and utilization
10.1016/S0014-5793(03)01077-9 FEBS Lett
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