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Description
Treatment duration differs significantly between the two options
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Normal human epidermal melanocytes (PomoCell, Cat #C-12413) were cultured in Melanocyte Basal Medium (PomoCell), including Melanocyte Growth Medium SupplementMix (PomoCell)

Recent evidence has revealed mitochondrial dysfunction in RA PBMCs, involving reduced ATP, disrupted m, elevated ROS, and upregulated ROMO1/OMA1 expression ( 2 O 2 -induced) upregulates MST1 expression in RA-FLSs, triggering mitochondrial dysfunction and apoptosis ( Taken together, mitochondrial metabolism reprogramming not only plays a key role in RA pathophysiology, but may be a promising potential target for future treatment of RA

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The catechol moieties of Tiron bind tightly to Fe + , resulting in a well-defined complex chemically represented as [Fe(C 6 H 4 Na 2 O 8 S 2 )] + , as illustrated in Scheme 1
