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On the other hand, in the placebo group, no significant changes in terms of weight, serum levels of FBS, insulin concentrations and lipid profile were found (Table 4)

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Elevated insulin levels cause an increase in insulin-like growth factor (IGF-1) and a decrease in insulin-like growth factor-binding protein 3 (IGFBP-3) (182)

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Adequate intake of this mineral is needed for maternal thyroid hormone production, and thyroid hormone is needed for myelination of the central nervous system and is thus essential for normal fetal brain development (147)

In aggregate, studies to date demonstrate that ZDV causes dysregulation of the carnitine pool leading to reduced intracellular levels