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Description

At the severe end of this spectrum, persistent energy deficiency may lead to functional hypothalamic amenorrhea (FHA), characterized by suppression of GnRH pulsatility and consequent disruption of ovulatory function, representing a reversible but clinically significant manifestation of energy-conserving neuroendocrine adaptation [90]

These findings underscore that JAKSTAT3 signaling broadly regulates astrocytic reactivity across contexts, highlighting the need for refined biomarkers to distinguish adaptive from maladaptive states 140

The same sample volume and measurement settings were used as described above

In order to provide solutions to the warfighter more rapidly, the Department of War, or DoW, releases three recurring Joint DoW Broad Agency Announcements, also referred to as BAAs, or Commercial Solutions Openings, also referred to as CSOs, each year for both SBIR and STTR programs