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RCT (Frye et al., 2016) A 12-week double-blind trial evaluated high-dose leucovorin in children with ASD and language delay [1]

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Despite its known effects, the physiological role of DSIP remains unclear, partly due to the lack of identification of its gene and receptor

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A number of researchers have called for the replacement of cyanocobalamin in supplements with other, safer forms of vitamin B12 listed above
