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Effects of testosterone on muscle strength, physical function, body composition, and quality of life in intermediate-frail and frail elderly men: a randomized, double-blind, placebo-controlled study

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PET studies have detected glucose hypometabolism in the frontal, motor, and occipital cortices [44]

Based on evidence of the dependence of metastatic prostate cancer on ROS [57, 58], this phenomenon could be a prostate cancer-mediated mechanism to maintain ROS levels in the tumor microenvironment, though this will need to be examined further
