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Therefore, use of rhEPO for treatment of tissue injury is limited by the potential side effects of increased erythrocyte mass and endothelial cell activation, which, in combination with activated platelet production, predisposes to thrombosis (6,7)

Men with serious cardiovascular disease such as uncontrolled high blood pressure, recent heart attack, heart failure, or unstable chest pain should not start peptide therapy without medical clearance

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For immunohistochemical staining, the tissue sections were inactivated by endogenous peroxidase with 3% hydrogen peroxide for 10 min and blocked with goat serum for 30 min

In another study, Alexandra et al., using OCT-A, found that after long-term VEGF inhibition, relapse was characterized by sub-RPE neovascularization 90

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