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Our data suggest that BT upregulates the genes involved in mitoplasticity, particularly genes involved in response to physiological stress (PGC1, HIF1), mitochondrial fission (DRP1, FIS1), mitophagy (PINK1, LC3, PTEN), oxidative stress (UCP2, NRF2, SOD2) as well as energy metabolism (mTOR, AMPK, SIRT3)

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J Thorac Cardiovasc Surg 132(6):1488-9, 2006

Mushrooms Demystified: A Comprehensive Guide to the Fleshy Fungi (2nd ed.)

Superoxide anions are potent reactive oxygen species (ROS) that can cause significant damage to cellular components, including DNA, proteins, and lipids, if not properly scavenged