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Experimental evidence supporting extrinsic Fas-mediated eryptosis suggests that eryptosis can be induced by external perturbations

When skin skews towards an alkaline pH, it can become dry and show signs of premature ageing such as fine lines, wrinkles, and hyperpigmentation

[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Sinclair KD, Allegrucci C, Singh R, Gardner DS, Sebastian S, Bispham J, Thurston A, Huntley JF, Rees WD, Maloney CA, Lea RG, Craigon J, McEvoy TG, Young LE