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Although clinical diagnosis relies on the presence of bradykinesia and other cardinal motor features, Parkinson disease is associated with many non-motor symptoms that add to overall disability

DR diagnoses and vitreoretinal interventions served as the primary outcomes

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CrossRef Distinct From the Adult Paradigm: Re-Evaluate the Pathophysiological and Therapeutic Framework in Children and Adolescent Hyperlipidaemia Yuan Xu, Hao Yang, Qianru Xu, Xiaomiao Yu, Siyu Dai, Xingwei Zhang, Weiyan Shen, Xudong Zhu Current Obesity Reports.2026;[Epub] CrossRef Incretin-based Agents and Metabolic Dysfunction-associated Steatotic Liver Disease Emir Muzurovi, Martin Haluzik, Ludek Horvth, Bogdan Vlacho, Didac Mauricio Current Pharmaceutical Design.2026

Thus, a functional overexpression of MnSOD, caused by presence of the Ala variant, combined with a potential deficiency of GPx-1, caused by the Leu variant, could potentially create a redox imbalance leading to enhanced hydrogen peroxide flux