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[DOI] [PubMed] [Google Scholar] 61.Santiago L.Y., Clavijo-Alvarez J., Brayfield C., Rubin J.P., Marra K.G

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3537 It has been proposed that metformin and phenformin inhibit thiamine absorption through inhibition of the human thiamine transporter (THTR2) in the small intestine, 38 a finding recently confirmed to be clinically relevant, 39 particularly in at-risk populations

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doi: 10.1111/ene.12846

The uninhibited GATOR2 then interacts with other cellular machinery (Rag GTPases) to successfully localize and activate mTORC1 at the surface of the cell's lysosomes
