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The mechanism involved phosphorylation of the CDK inhibitor p27 at T157, promoting cytoplasmic translocation of p27 and effectively neutralizing its nuclear cell-cycle-arrest activity

An mtDNA mutation accelerates liver aging by interfering with the ROS response and mitochondrial life cycle

Patient stratification includes the classification of tissue and gene mutation subtypes, aiming to achieve individualized medical treatment and maximize the benefits for each patient

doi:10.1016/j.arr.2015.12.007 Gltrk MT, nal ZN, smi O, imen MB, nal M

(2008) in mPFC LFO of anesthetized rats

Monosodium Urate Crystals Induce Extracellular DNA Traps in Neutrophils, Eosinophils, and Basophils But Not in Mononuclear Cells
