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Moreover, inhibition of the PI3K/Akt activation restrained the GHK-induced upregulation of miR-146a-3p and the downregulation of AQP4

This distances the [2Fe-2S] cluster from the CoQH anion, making electron transfer more favorable through the low-potential redox chain

GHK-Cu also activates Wnt/beta-catenin signaling, a critical pathway for hair follicle cycling