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In addition, a somatic exonuclease domain mutation in POLE would be involved in phenocopying defective MMR DNA in 25% of unexplained endometrial cancers with MSI [102]

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However, its low sensitivity makes it unsuitable for lung cancer screening in the general population (Liu et al., 2021)

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evaluated intraduodenal (ID) infusions of glutamine (7.5 or 15 g) or saline over 30 min in healthy subjects and 15 g glutamine or saline in T2DM patients followed by an ID infusion of glucose over 100 min [36]
