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A statistically significant increase in cancer was observed in rats receiving semaglutide at all dose levels (greater than 2X human exposure)

They would also need to be modified so that they can stay in the bloodstream long enough to be effective, which Pentelutes lab is also working on

10.1148/radiol.11101942 16 ChenX.KangR.KroemerG.TangD

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In practical terms, this means it stimulates the growth of new blood vessels

Psychiatry 81 , 424433 (2017)