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Selective protection of nuclear thioredoxin-1 and glutathione redox systems against oxidation during glucose and glutamine deficiency in human colonic epithelial cells

[DOI] [PMC free article] [PubMed] [Google Scholar] 284.Clemente-Surez VJ, Redondo-Flrez L, Beltrn-Velasco AI, Ramos-Campo DJ, Belinchn-deMiguel P, Martinez-Guardado I, Dalamitros AA, Yez-Seplveda R, Martn-Rodrguez A, Tornero-Aguilera JF

How It Works GHKCu is a naturally occurring copperbinding tripeptide that penetrates the stratum corneum and signals fibroblasts to produce more collagen, elastin, and glycosaminoglycans while regulating matrix metalloproteinases to reduce excessive collagen breakdown

This breaks the tripeptide into glutamate, cysteine, and glycine before absorption

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