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In addition to GLS inhibitors, strategies targeting the conversion of glutamate into -ketoglutarate, such as GDH inhibitors and aminotransferase inhibitors, have also been evaluated in preclinical models of breast cancer and neuroblastoma [103-105]

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For example, cholinergic neurons stimulate Ca2 + currents in intestinal epithelial cells, promoting their maturation and repair [408]

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