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PMID: 39680480 Nat Chem Biol 2025 Mar;21(3):371-382

IHH-4 and GLAG-66 cells were treated with 0, 1, 5, 10, 25, 50, 100, 200, 500 and 1000 g/mL of APS for 24, 48 and 72 h to detect the IC50 of APS

17 : 25962606 Ichijo H, Nishida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T, Takagi M, Matsumoto K, Miyazono K and Gotoh Y (1997) Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

These ROS inflict direct oxidative damage on submucosal vascular cells
Astaxanthin Is Able to Prevent Alcohol-Induced Dysfunction of Liver Mitochondria

Fisetin also attenuated inflammation by lowering TNF- and IL-6 levels, while enhancing antioxidant defense through increased GSH and superoxide dismutase (SOD) [123]
