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36 In people with type 2 diabetes and established cardiovascular disease, two years of low-dose semaglutide (0.5 or 1 mg) reduced the risk of a composite outcome of cardiovascular death, nonfatal myocardial infarction or nonfatal stroke by 26%, primarily driven by stroke reduction

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In people without diabetes, tirzepatide 5 to 15 mg once weekly for the treatment for obesity (SURMOUNT-1) resulted in substantial reductions in body weight (16.5% to 22.4%) over 72 weeks

[DOI] [PubMed] [Google Scholar] 122.Yukna R, Salinas TJ, Carr RF