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However NAPQI is the responsible of the toxic effects of acetaminophen

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[DOI] [PMC free article] [PubMed] [Google Scholar] 254.Gupta H., Youn G.S., Shin M.J., Suk K.T

290 Together, these examples indicate that nutritional deficiencies or insufficient protein cofactor incorporation, e.g., due to loss of function in specific transporters, cofactor chaperones, or the cofactor-binding sites of proteins themselves, may lead to dysproteostasis through effects on protein folding and stability

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Iran J Basic Med Sci 23(6):730736