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The impact of parasite infections on the course of multiple sclerosis

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[DOI] [PMC free article] [PubMed] [Google Scholar] 31.Dada R., Kumar M., Jesudasan R., Fernndez J.L., Goslvez J., Agarwal A

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Among them, glutathione peroxidase (GPx) stands out as it helps mitigate the harmful effects of ROS and inactivates hydrogen and lipid peroxides

Beside generation of ROS, cyclophosphamide inhibits the endogenous antioxidant pathways, in particular nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway, a master transcription factor for conserving redox homeostasis [19]