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At the same time, a poly(lactic-co-glycolic acid) (PLGA) nanovaccine co-delivering the adjuvant R837 and Luc-4T1 cell membrane antigen, with surface-exposed calreticulin, can induce active uptake by DCs thereby enhancing the anti-tumor effect (101)

Oxidative stress, neuroinflammation, and neuronal damage all impair sleep quality even when the circadian system is functioning

Lei W, Luo Y, Lei W, Luo Y, Yan K, Zhao S, Li Y, Qiu X, Zhou Y, Long H (2009) Abnormal DNA methylation in CD4+ T cells from patients with systemic lupus erythematosus, systemic sclerosis, and dermatomyositis

In addition, this study also showed that inhibiting glycolysis using 2-deoxy-D-glucose can reduce liver inflammation and fibrosis in liver-specific geranylgeranyl diphosphate synthase (GGPPS) knockout mice [154]

105 Neoalbaconol down-regulates E3 ubiquitin ligases cellular inhibitors of apoptosis protein 1/2 (cIAP1/2) and TRAFs to abolish K63-linked ubiquitination on RIPK1