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8 Conclusion and future perspectives The recognition of ferroptosis as a critical mechanistic link between dysregulated metabolism, immune activation, and chronic airway inflammation establishes the Ferroptosis-Immune-Metabolic Axis as a transformative conceptual framework for understanding asthma pathogenesis

Anal Bioanal Chem 413 , 13371351 (2021)

however, further analysis is necessary to confirm a role for the Ku antigen complex and ORE sequences in modulating hypoxic responses in vivo and in cells other than cardiomyocytes and to define the mechanism by which they respond to oxygen tension
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Essential mediators of vascular development

Since the importance of complement system in cancer biology has been demonstrated, the role of C5a-C5aR1 axis in the pathogenesis of different types of cancer has been explored in several studies along with the potential therapeutic effect of its inhibition
