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Results ALA is able to enter the bloodbrain barrier due to its distinctive combination of hydrophilic and hydrophobic characteristics, enabling it to directly affect brain regions

All administrations were done orally for once

FOXO4-DRI is a peptide used in senescence research

By concurrently depleting glutathione and perturbing copper homeostasis, EsCu@NPs elicit reinforced cuproptosis stress that is converted into immunogenic cell death

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