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Nature 409 , 729733 (2001)

Tolerance has not been observed in clinical use

[DOI] [PubMed] [Google Scholar] 81.Smith BM, Smith JM, Tsai JH

Clinical trials have shown that patients on Semaglutide can lose up to 15% of their body weight over 68 weeks, whereas Phentermine users typically see an average loss of 5-10% of body weight over a shorter period

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