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For example, it promotes protein folding in the ER by regulating the expression of chaperone proteins such as GRP78 and PDI

Further, the inherent limitations of studying topical dosing in murine models necessitates further studies of pharmacokinetics and efficacy in larger species, as well as ocular safety and tolerability studies

It functions as an antioxidant, though its antioxidant activity is slightly lower compared to other carotenoids (Mortensen and Skibsted 1997

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doi:10.1080/02652030310001639521 [DOI] [PubMed] [Google Scholar] 12.Chapot-Chartier MP, Kulakauskas S

Neutrophil elastase in the development of nephrogenic systemic fibrosis (NSF)-like skin lesion in renal failure mouse model