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History [edit] Descriptions of deficiency effects [edit] Between 1849 and 1887, Thomas Addison described a case of pernicious anemia, William Osler and William Gardner first described a case of neuropathy, Hayem described large red cells in the peripheral blood in this condition, which he called "giant blood corpuscles" (now called macrocytes), Paul Ehrlich identified megaloblasts in the bone marrow, and Ludwig Lichtheim described a case of myelopathy

Semax is a synthetic peptide derived from ACTH that enhances cognition and protects the brain without hormonal effects

It also appeared to increase energy due to increased sleeping time

The D-series code (for example D50.9 for iron deficiency) may be added as a secondary to specify the anemia type

Cyano B12, however, doesnt absorb well and requires a methyl group to detoxify it before it can ever convert to a useful form

KOR activation reduces glutamate release onto mPFC pyramidal neurons (Tejeda et al., 2013)