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doi:10.1155/2014/132564

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RhoA/ROCK exists in many tissues throughout the human body and participates in regulating a variety of physiological functions, including but not limited to, cell contraction, migration, proliferation, and adhesion

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3.4 PI3K/AKT pathway Upon receptor binding by insulin and inflammation, the PI3K/AKT pathway is activated, acting as an essential oncogenic mechanism controlling metabolism, cell growth, and survival

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it monitors each individual cell

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