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Studies revealed that by increasing the concentrations of the cytosolic cysteine, and thus glutathione of monocytes and macrophages using a synthetic form of cysteine called NAC, blocks H 2 O 2 mediated activation of NF-kB, and thus pro-inflammatory cytokines (tumor necrosis factors [TNF]-, interleukin [IL]-1 and IL-6) by this route

[DOI] [PubMed] [Google Scholar] 60.Duan R., Wang T., Li Z., Jiang L., Yu X., He D., Tao T., Liu X., Huang Z., Feng L., et al

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These metabolites have been shown to exert neuroprotective effects by maintaining the integrity of the bloodbrain barrier (BBB), modulating immune responses, and promoting neuronal health (Wang et al., 2018)