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Further studies are needed to assess the long-term effects of coffee or caffeine on vascular function and CV events in a large population, including subjects with high CV risk factors and patients with a history of myocardial infarction or stroke

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Non-limiting examples of NHR N1 , in which R N1 is optionally substituted alkyl include: optionally substituted alkylamino, a proteinogenic amino acid, a non-proteinogenic amino acid, a C 1-6 alkyl ester of a proteinogenic amino acid, and a C 1-6 alkyl ester of a non-proteinogenic amino acid

[DOI] [PubMed] [Google Scholar] 297.Tsai YL, Lin TL, Chang CJ, Wu TR, Lai WF, Lu CC, et al

Moreover, these mechanisms provide the provide specific molecular pathways that link cellular pathology with the systemic axes discussed earlier

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