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Evaluation of the antidepressant-like activity of Convolvulus pluricaulis Choisy in the mouse forced swim and tail suspension tests

Glutathione plays a central role in the bodys antioxidant defense system, neutralizing harmful free radicals that can damage cells and tissues

doi: 10.1074/jbc.M501751200

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We conducted a safety evaluation of the candidate compounds, followed by an assessment of their therapeutic effects in APP/PS1 transgenic mice

[49] Of interest, a peptide therapy targeting pro-inflammatory tumor necrosis factor alpha (TNF-) induced the generation of T regs and reduced inflammation in a mouse model of collagen induced arthritis