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When they are mutated, aberrantly expressed or driven by aberrant upstream signals, writers, readers and erasers of histone marks can affect the expression patterns of genes that lead to or even drive and maintain disease states

However, it remains technically challenging due to the complex anatomy and proximity to critical vascular structures

doi: 10.1038/s41598-022-17645-7 135 WuKLinKLiXYuanXXuPNiPet al

However, the aforementioned mutation was related to a lower frequency of diastolic dysfunction in patients with a normal left ventricular ejection fraction (LVEF)

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Dihexa has not been tested in large-scale human clinical trials and does not hold FDA approval for any indication