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If irritation appears during this phase, reduce application frequency rather than abandoning the product entirely

Elmore et al., 2001

Moreover, reducing the senescent testosterone-producing cell burden may leave a higher proportion of cells that still express the enzymes needed to make testosterone, or may allow remaining testosterone-producing cells to restore some of that enzyme expression

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This sensation, called paresthesia, can result from nerve involvement related to a B12 deficiency, often in the hands, legs, or feet

Rheumatoid arthritis Rheumatoid arthritis involves autoimmune attack against the synovial membrane lining the joints