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Its cellular regulation is tightly controlled by zinc transporters, particularly the Zip (Zrt/Irt-like protein) family (Zip1-14/SLC39 A1-14), which facilitates zinc influx into the cytoplasm, and the ZnT (Zinc Transporter) family (ZnT1-10/SLC30 A1-10), which mediates zinc efflux to maintain homeostasis

Therefore, noting the lack of spontaneous oxidation of free GSH between the two EDTA-treated samples stored at 80 o C, this result also suggests that the differences in GSH between the heparinized plasma (Preparation Condition 1) and deproteinized EDTA-treated plasma (Preparation Condition 2) are due to spontaneous oxidation of free GSH occurring in the heparinized plasma prior to the deproteinization process

[DOI] [PMC free article] [PubMed] [Google Scholar] 157.Bettermann E.L., Hartman T.J., Easley K.A., Ferranti E.P., Jones D.P., Quyyumi A.A., Vaccarino V., Ziegler T.R., Alvarez J.A