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Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences
Moreover, innovative drug delivery strategies, including focused ultrasound, implantable drug-delivery systems, and engineered nanoparticles, hold potential for enhancing the bioavailability and therapeutic efficacy of treatments

In a model of amyotrophic lateral sclerosis (ALS) caused by C9orf72 gene mutations, the pathogenic poly-dipeptide GA50 directly binds to and inhibits SQOR, leading to excessive NLRP3 inflammasome activation in microglia and consequent mitochondrial dysfunction (Fu et al., 2023)

Gaurav R, Lejeune FX, Santin MD, Valabrgue R, Prot JB, Pyatigorskaya N, et al

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The GBU-38's detonation ignited ISIS explosive materials that ISIS had previously emplaced in the structure
