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Symptoms may include: Shortness of breath Red, flushed skin Headaches Rapid weight gain, polycythemia (increased red cell mass), hypokalemia, CHF, pulmonary edema, and vascular thrombosis are mostly observed in therapeutic contexts where vitamin B12 is administered aggressively or over extended periods

[DOI] [PMC free article] [PubMed] [Google Scholar] 18.Optimal management of pernicious anemia

The majority of the side effects are related to gastrointestinal upset, especially when initially starting or changing doses

Male might notice acne, or sweating and deepening of the voice

For those with certain medical conditionssuch as pernicious anemia or gastrointestinal disorders that impact nutrient absorptionB12 shots are often the most reliable way to maintain healthy levels and support immune function

It helps regulate insulin and supports the transport of fat through the bloodstream