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Of which, compounds 17 19 were strongly cytotoxic to the HeLa and HL-60 cells with IC 50 values ranging from 0.1 to 3.9 mol/L whilst 20 22 were inactive

Neurobiol Aging 95:168175 Sies H (1999) Glutathione and its role in cellular functions

In addition, endo-EVs consisted of a three-fold reduced amount of ionizable lipid compounds critical for LNP production but potentially toxic per mRNA compared to LNPs

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[DOI] [PMC free article] [PubMed] [Google Scholar] 565.Lizk B., Szarka A., Kim Y., Choi K.-s., Nmeth C.E., Marcolongo P., Benedetti A., Bnhegyi G., Margittai