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GSH deficiency results in the activation of von Willebrand Factor (Violi et al., 2017): notably, hypercoagulation is a prominent life-threatening complication in COVID-19 patients ( Notably, low GSH plasma levels have been identified along with three other clinical indicators (age, CD3 ratio, and total protein) as a predictor of the severe/critical symptoms of COVID-19 infected patients (Sun et al., 2020)

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Signal Transduct Target Ther 7(1):391 Guo Z, Wang M, Ying X, Yuan J, Wang C, Zhang W, Tian S, Yan X (2023a) Caloric restriction increases the resistance of aged heart to myocardial ischemia/reperfusion injury via modulating AMPKSIRT1PGC1a energy metabolism pathway

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