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( Probiotic applications are increasingly guided by the principles of personalized nutrition, integrating nutrigenetics, nutrigenomics, and precision medicine ( Human health is intimately linked to the diverse ecosystems of bacteria, fungi, viruses, and yeasts that coexist symbiotically on and within the body ( In 2018, Dieterich et al

Our bodies are constantly producing free radicals (uncharged, highly reactive molecules with unpaired electrons)

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Figure 11 3.14 The impact of C75 on the lipid metabolism in vivo Finally, immunohistochemical analysis showed that, except for Acsl1 ( Figures 11K, Q ), the expression of lipid metabolism-related genes Fasn ( Figures 11G, M ), Scd1 ( Figures 11H, N ), Dgat2 ( Figures 11I, O ), Acaca ( Figures 11J, P ), and PPAR- ( Figures 11L, R ) were significantly decreased in the SHR+C75 group compared to the SHR+Vehicle group

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132 Concurrently, ROS, particularly OH, initiate lipid peroxidation by attacking polyunsaturated fatty acids (PUFAs) within cellular membranes