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Immune checkpoint inhibitors (ICIs) have become the treatment of choice for recurrent or metastatic cancers, with the most widely used being anti-cytotoxic T lymphocyte associated protein 4 (CTLA4) and anti-programmed cell death protein-1 (PD1) antibodies [76]

[DOI] [PubMed] [Google Scholar] 30.Lawless M.J., Pettersson J.R., Rule G.S., Lanni F., Saxena S

It plays a key role in transporting long-chain fatty acids into the mitochondria, where they can be used for energy

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RAG-01 is another saRNA candidate drug designed to treat bladder cancer by activating the expression of the human cyclin-dependent kinase inhibitor 1 A

148 demonstrated the epigenetic inactivation of ASS1 as a factor of response to platinum chemotherapy and imply that transcriptional silencing of ASS1 contributes to treatment failure and clinical relapse in EOC patients