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Effects of leptin on HPG axis and reproductive function in male rat in simulated altitude of 5500 m hypoxia environment

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showed that SB administration (1 g/kg/d) inhibited the activation of the cyclooxygenase-2 (COX-2)/prostaglandin E2 (PGE2) pathway in a HDAC5/HDAC6-dependent manner, contributing to reducing Ang II-induced heart hypertrophy, mean arterial pressure and inflammation (Zhang et al., 2019)

10.1371/journal.pone.0166061 6 AvinerR.LeeT.-T.MastoV