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Tezel G, Yang X, Cai J (2005) Proteomic identification of oxidatively modified retinal proteins in a chronic pressure-induced rat model of glaucoma

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However, certain types of tissues or organs can be irreversibly damaged based on the dose and area of exposure [242]

For example, osteoporotic and senile bone defects are typically characterized by reduced vascularization and impaired bone marrow niches, requiring scaffolds that provide long-term mechanical support and pro-angiogenic activity

While this theory is yet to be comprehensively tested in FM, preliminary evidence has been reported in other conditions including chronic fatigue syndrome (100, 101)