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In clinical trials, 6-16% of participants discontinued retatrutide due to gastrointestinal adverse events (Jastreboff et al., NEJM, 2023)

Since human clinical trials are essentially nonexistent, the available data comes from anecdotal reports from the biohacking community
Find articles by Lei, X
Recurrent gout attacks that arent treated may involve more joints, last longer, and become increasingly severe over time
These symptoms are an important catalyst in the resumption of use [41, 42], undermining the success of completing detoxification, which, in practice, is often a necessary antecedent to engaging in psychosocial treatment options, such as residential rehabilitation or counselling, that facilitate longer-term recovery
It is a 29-amino acid polypeptide representing the 129 fragment from endogenous human GHRH, thought to be the shortest fully functional fragment of GHRH
