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Further evidence for this hypothesis comes from recent yeast two-hybrid studies performed with enzymes from sweet peony, where the arGST Ps GSTF3 was found to interact with Ps DFR, the dihydroflavonol reductase catalysing the formation of 3,4- cis -leucocyanidin ( 6 ) 47

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Tesamorelin is an FDA-approved synthetic growth hormonereleasing hormone analogue that stimulates IGF-1 production to reduce visceral abdominal fat in HIV-associated lipodystrophy, though its use outside this population remains unproven

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