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[10] Furthermore two mutations in the TrxR2 gene are found in patients diagnosed with DCM and not in a control population

Linking diabetic complications to sorbitol oxidation, oxidative stress and metabolic suppression

This evidence suggested that high glucose induces the activation of PSCs and promotes their proliferation, leading to increased ECM secretion

doi:10.1136/jnnp-2014-307601 Kozak HH, Dundar MA, Uca AU, et al

Fiszman G, Cattaneo V, de la Torre E, Espaol A, Colombo L, Sacerdote de Lustig E, Sales ME

Polaka, S., Katare, P
