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Furthermore, SCFAs might regulate energy homeostasis through binding to the G protein-coupled receptors (GPCRs), GPR41 and GPR43, on intestinal epithelial cells (56), namely, peptide YY (PYY) (59) and glucagon-like peptides 1 and 2 (GLP-1 and GLP-2) (60)

Decombaz, J., Deriaz, O., Acheson, K., Gmuender, B., and Jequier, E

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G., Emma, F., Sorino, P., De, Palo T., Lavoratti, G., Turrini, Dertenois L., Cassanello, M., Cerone, R., and Perfumo, F

A landmark 2024 patient-reported outcomes study published in the Proceedings of the National Academy of Sciences (PNAS) provided compelling real-world data on the efficacy of various treatments for Long COVID and ME/CFS