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Lactylation-driven IGF2BP3-mediated serine metabolism reprogramming and RNA m6A-modification promotes lenvatinib resistance in HCC

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Our present data showed a higher level of TAUT protein in the LC-treated cells compared to that in the control cells, indicating that LC markedly increases the TAU uptake by VSMCs, resulting in an increased intracellular TAU level

Production of neurotransmitters

Interestingly, in our study all groups undergoing the VLCKD presented a reduction of CRP concentrations, a well-known marker of inflammation