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P.AlvesM.WolffsohnJ

ROS accumulation can directly affect DNA integrity, and ROS-mediated DNA damage could favor the initiation stage of tumorigenesis

[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Mizuno K., Tanaka M., Nozaki S., Mizuma H., Ataka S., Tahara T., Sugino T., Shirai T., Kajimoto Y., Kuratsune H., et al

BPC-157 is commonly discussed for more localised repair-related pathways, while TB-500 is often associated with wider systemic recovery mechanisms

colonization with SCFA-producing strains (such as Clostridium tyrobutyricum and Bacteroides) reversed these effects (105108)

Importantly, directly comparing the single KO phenotype across four conditions highlighted 19 nutrient-dependent phenotypes that are otherwise mild in any single condition, which we termed GxE interactions (Fig
