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Research has revealed that ER stress is associated with nephrotoxicity induced by MTX as well as hepatic stellate cells (HSCs) activation (Koo et al., 2016

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doi: 10.1071/PP96118 22 HasanuzzamanM.ShabalaL.BrodribbT

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Anti-apoptotic effects of novel phenolic antioxidant isolated from the Pacific oyster ( Crassostrea gigas ) on cultured human hepatocytes under oxidative stress