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The diversity of epitopes that can be bound by antibodies capable of eliciting Fc-dependent effector functions (mediated by both neutralizing and non-neutralizing antibodies) may explain the overall lack of antigenic escape relative to the more discrete epitopes that contribute to neutralization

Under a pharmacological point of view, Glutaminase represents an important target for anticancer therapy (82)

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[DOI] [PubMed] [Google Scholar] 17.Zhang W, Tung CH

Mechanism Investigation: Examine whether acetylation affects upstream signaling pathways differently than unmodified form

For Pf AMA1 (1Z40), furans: Nitrofurantoin, Prazosin, Furosemide, Ranitidine( n = 4) and pyrazoles: Rimonabant, Celecoxib, Ruxolitinib, Pyrazofurin ( n = 4) were used as reference inhibtors